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Clinical trials for Musculoskeletal System

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
  • clinical trials conducted outside the EU/EEA that are linked to European paediatric-medicine development

    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
    Examples: Cancer AND drug name. Pneumonia AND sponsor name.
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    524 result(s) found for: Musculoskeletal System. Displaying page 1 of 27.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2010-018975-13 Sponsor Protocol Number: ROSA_10 Start Date*: 2010-02-24
    Sponsor Name:ISTITUTO ORTOPEDICO RIZZOLI
    Full Title: EFFICACY OF ROSE HIP IN TREATMENT OF PAIN IN PATIENTS WITH COXARTHROSIS
    Medical condition: PATIENTS TO BE IMPLANTED WITH HIP PROSTHESIS
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2010-018904-94 Sponsor Protocol Number: 2010-018904-94 Start Date*: 2010-05-31
    Sponsor Name:FONDAZIONE SALVATORE MAUGERI - CLINICA DEL LAVORO E DELLA RIABILITAZIONE
    Full Title: EFFICACY AND SAFETY OF INTRAMUSCULAR NERIDRONATE IN OSTEOPOROTIC PATIENTS AFFECTED BY PARKINSON'S DISEASE
    Medical condition: Osteoporosis in patients affected by Parkinson's disaease at the stages 1-2-3-4 following Hoehn and Yahr criteria
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-007479-18 Sponsor Protocol Number: PROTESI Start Date*: 2008-01-23
    Sponsor Name:OSPEDALE S. RAFFAELE
    Full Title: Postoperative analgesia in major ortopedic surgery: continuos epidural perfusion with laevobupivacaine 0.125% vs continuos epidural perfusion with laevobupivacaine 0.125% + sufentanil 0.5 gamma/ml.
    Medical condition: patients undergoing to surgery for hip and knee prothesis (first implantation)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2007-000421-21 Sponsor Protocol Number: CROCIATO Start Date*: 2007-02-20
    Sponsor Name:OSPEDALE S. RAFFAELE
    Full Title: PROSPECTIVE, RANDOMIZED, DUOBLE BLIND COMPARISON BETWEEN SUBARACNOID ANAESTHESIA AND SUBARACNOID ANAESTHESIA WITH BLOCK OF FEMORAL NERVE IN PATIENTS UNDERGOING SURGERY FOR ANTERIOR LIGAMENT REPAIR.
    Medical condition: PATIENTS UNDERGOING SURGERY FOR CRUSADER ANTERIOR LIGAMENT
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2012-005357-23 Sponsor Protocol Number: 01 Start Date*: 2013-01-27
    Sponsor Name:AUSL VITERBO
    Full Title: Preventing injection pain by Clostridium Histolyticum Collagenase Administration for teatment of Dupuytrens contracture
    Medical condition: Dupuytren s Disease
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-004258-24 Sponsor Protocol Number: FBA Start Date*: 2011-09-19
    Sponsor Name:UNIVERSITA' CAMPUS BIOMEDICO
    Full Title: Clinical trial to study application of MESNA for infiltration into the epidural ''Failed Back Syndrome'' (FBS)
    Medical condition: Failed Back Syndrome
    Disease: Version SOC Term Classification Code Term Level
    14.0 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-004682-32 Sponsor Protocol Number: 2011-09 Start Date*: 2012-02-07
    Sponsor Name:FONDAZIONE ISTITUTO SAN RAFFAELE-G.GIGLIO
    Full Title: Intra-articular injection of botulinum toxin type A in hemiplegic shoulder pain: a multicentric, double blind randomised, versus steroid study.
    Medical condition: hemiplegic shoulder pain
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2012-004890-25 Sponsor Protocol Number: BOLD01 Start Date*: 2013-01-14
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA S. MARIA DELLA MISERICORDIA DI UDINE
    Full Title: Botulinum Toxin Serotype A randomized double-blind, placebo controlled multicentre study for degenerative coxarthrosis.
    Medical condition: coxarthrosis
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2012-000866-40 Sponsor Protocol Number: 2012-000866-40 Start Date*: 2012-03-12
    Sponsor Name:ISTITUTO ORTOPEDICO RIZZOLI
    Full Title: Evaluation of the efficacy and suppression of the hypothalamic-pituitary-adrenal axis resulting in intrabursale single administration of cortisone in patients with calcific tendonitis of the rotato...
    Medical condition: calcific tendonitis of the rotator cuff
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-003185-33 Sponsor Protocol Number: INRCA-02-2011 Start Date*: 2011-10-13
    Sponsor Name:ISTITUTO NAZIONALE DI RICOVERO E CURA PER ANZIANI IRCCS
    Full Title: Prospective, controlled, randomized, blind study to evaluate the effects of intramuscular-paravertebral injections of an oxygen-ozone (O2-O3) mixture in patients with lumbar pain aged 65 or older
    Medical condition: subjects aged 65 or older with lumbar pain and discopathy for at least 6 weeks
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-004673-17 Sponsor Protocol Number: PHRC IR08 - Pr. FOURNIER Start Date*: 2009-03-23
    Sponsor Name:CHU d'Amiens
    Full Title: Comparaison du nicotinamide et du sevelamer hydrochloride sur le contrôle de la phosphatémie des hémodialysés chroniques
    Medical condition: Ostéodystrophie rénale
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-003372-18 Sponsor Protocol Number: NERI-AS001-07 Start Date*: 2007-12-03
    Sponsor Name:ABIOGEN PHARMA
    Full Title: A randomised, double-blind, placebo controlled study to assess the safety and the efficacy of neridronate 100 mg - 4 i.v. infusions in a course of 10 days treatment - in patients with algodystrophi...
    Medical condition: Algodystrophic Syndrome
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2004-000362-12 Sponsor Protocol Number: K-832-2.01EU Start Date*: 2004-07-23
    Sponsor Name:Kowa Research Europe Ltd
    Full Title: A Double-Blind, Randomised, Dose-Ranging Study to Compare K-832 with Placebo in the treatment of Patients with Active Rheumatoid Arthritis
    Medical condition: Rheumatoid Arthritis
    Disease: Version SOC Term Classification Code Term Level
    6.0 10028395 LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: CZ (Completed)
    Trial results: View results
    EudraCT Number: 2010-018600-87 Sponsor Protocol Number: Peri-Trauma Start Date*: 2010-02-24
    Sponsor Name:AZIENDA OSPEDALIERA MAGGIORE DELLA CARITA` DI NOVARA
    Full Title: POST-OPERATIVE PAIN CONTROL OF PEDIATRIC PATIENTS UNDERWENT ORTHOPEDIC SURGERY: COMPARISON OF INTRAVENOUS ANALGESIA AND ONE-SHOT EPIDURAL LUMBAR NERVE BLOCK.
    Medical condition: POST-OPERATIVE PAIN CONTROL OF PEDIATRIC PATIENTS UNDERWENT ORTHOPEDIC SURGERY
    Disease: Version SOC Term Classification Code Term Level
    9.1 10028395 SOC
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-017160-17 Sponsor Protocol Number: ALGO-01 Start Date*: 2010-02-24
    Sponsor Name:ISTITUTI ORTOPEDICI RIZZOLI
    Full Title: NSAID USED IN MESOTHERAPY VS NSAID INTRAMUSCOLAR INJECTION IN algodistrophy TREATMENT: A RANDOMIZED, CONTROLLED STUDY
    Medical condition: SUFFERED FROM ALGODISTROPHY PATIENTS
    Disease: Version SOC Term Classification Code Term Level
    9.1 10029205 SOC
    9.1 10028395 SOC
    Population Age: Children, Adolescents, Under 18, Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2006-003146-41 Sponsor Protocol Number: 50021031-2 Start Date*: 2007-03-08
    Sponsor Name:Charité-Universitätsmedizin Berlin; Department of Rheumatology and Clinical Immunology
    Full Title: A CONTROLLED RANDOMIZED DOUBLE-BLIND MULTICENTER STUDY COMPARING TWO THERAPY STRATEGIES IN DMARD-NAIVE EARLY RHEUMATOID ARTHRITIS PATIENTS OVER 48 WEEKS: INDUCTION THERAPY WITH ADALIMUMAB AND METHO...
    Medical condition: Musculoskeletal disorders
    Disease: Version SOC Term Classification Code Term Level
    8.1 10048592 Musculoskeletal disorder LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-002010-39 Sponsor Protocol Number: ORTHO-2 Start Date*: 2014-04-11
    Sponsor Name:Universidad Autónoma de Madrid
    Full Title: Evaluation of safety and feasibility of bone marrow derived autologous MSCs to enhance bone healing in patients with avascular necrosis of femoral head
    Medical condition: Early avascular necrosis of the femoral head (MRI diagnosis): Ficat and Arlet 0, 1, or 2 (Steinberg stages 0, I, IIA, IIB, or IIC)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10003860 Avascular necrosis femoral head LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Ongoing) IT (Ongoing) ES (Ongoing) RO (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-005661-20 Sponsor Protocol Number: SKP-021-01-11 Start Date*: 2012-07-13
    Sponsor Name:PROMO INTERNATIONAL SRL
    Full Title: A double-blind, randomised, parallel group, active controlled, multicentre study to assess the therapeutic non-inferiority of SKP-021, a 0.3% ketoprofen patch, versus diclofenac sodium patch in pat...
    Medical condition: patients with painful and inflammatory conditions (e.g.: back pain, bruise, contusion, sprain, strains)
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2012-002566-12 Sponsor Protocol Number: DSC/11/2357/43 Start Date*: 2013-02-04
    Sponsor Name:ITALFARMACO
    Full Title: A Two-Part Study to Assess the Safety and Tolerability, Pharmacokinetics, and Effects on Histology and Different Clinical Parameters of Givinostat in Ambulant Children with Duchenne Muscular Dystrophy
    Medical condition: Duchenne Muscular Dystrophy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Children, Under 18 Gender: Male
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2010-019109-40 Sponsor Protocol Number: XC0409 Start Date*: 2011-03-25
    Sponsor Name:Xenome Ltd
    Full Title: A multicenter, randomized, observer-blinded, single-dose, placebo-controlled, sequential cohort study of the efficacy and safety of Xen2174 in subjects following bunionectomy surgery
    Medical condition: Moderate to severe acute post-operative pain in subjects following primary unilateral first metatarsal bunionectomy
    Disease: Version SOC Term Classification Code Term Level
    14.1 10028395 - Musculoskeletal and connective tissue disorders 10028395 Musculoskeletal and connective tissue disorders SOC
    Population Age: Adults Gender: Male, Female
    Trial protocol: BG (Completed)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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